Insulin-Like Growth Factor-1 and Vascular Endothelial Growth Factor in Malignant and Benign Biliary Obstructions
نویسندگان
چکیده
منابع مشابه
[Vascular endothelial growth factor in benign and malignant pleural effusions].
OBJECTIVE Vascular endothelial growth factor (VEGF) is a potent inducer of capillary permeability and its role as a crucial mediator in pleural fluid formation has been established. This study was conducted to assess the usefulness of VEGF for diagnosing malignant and non-malignant pleural effusions of various causes. PATIENTS AND METHODS VEGF levels in pleural effusions collected from 52 pat...
متن کاملPatterns of Vascular Endothelial Growth Factor Expression in Hematopoietic Malignant Cells
Background and Objective: Vascular endothelial growth factor (VEGF) is a cytokine which is overexpressed in many malignant cancers including leukemia. VEGF plays an important role in tumor invasion and metastasis. Determination of the pattern of VEGF expression in human leukemic cell lines could be useful not only in screening of new antileukemic agents but also to study the mechanism of their ...
متن کاملEvaluation of Periodontal Disease Effect on the Expression of Vascular Endothelial Growth Factor and Nerve Growth Factor in Dental Pulp
Introduction: Researchers have always been interested in the close and mutual relationship between the pulp and periodontal tissues. Although the effects of pulpal disease on periodontium have been well known, the clear relationship between periodontitis and pulp has not been documented . It seems that bacteria and inflammatory products of periodontitis can affect pulp through accessory canals,...
متن کاملHypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion.
Hypoxia-induced stress plays a central role in retinal vascular disease and cancer. Increased hypoxia-inducible factor-1 alpha (Hif-1 alpha) expression leads to HIF-1 formation and the production of vascular endothelial growth factor (VEGF). Cytokines, including insulin-like growth factor-1 (IGF-1), also stimulate VEGF secretion. In this study, we examined the relationship between IGF-1 signali...
متن کاملThe Insulin-like Growth Factor-1 (G>A) and 5,10-methylenetetrahydrofolate Reductase (C677T) Gene Variants and the Serum Levels of Insulin-like Growth Factor-1, Insulin, and Homeostasis Model Assessment in Patients with Acne Vulgaris
Background & Objective: To find an association between gene variants of insulin-like growth factor-1 (IGF-1) and 5,10-methylenetetrahydrofolate reductase (MTHFR) with the risk of acne vulgaris (AV). Methods: In a case-control study, we investigated 150 AV patients and 148 healthy individuals (aged 18-25 years) for the IGF-1 G>A and MTHFR C677T polymorphis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The American Journal of the Medical Sciences
سال: 2016
ISSN: 0002-9629
DOI: 10.1016/j.amjms.2015.12.013